Current projects:

 

Nutritional protection against neuromuscular disease

Proteomic studies of spinal muscular atrophy

Identifying and Quantifying Growth Promoting Signals in the Developing Spinal Cord

Monoclonal antibody studies of congenital muscular dystrophies (alpha-dystroglycan & fukutin)

Monoclonal antibody studies of nesprins in cardiomyopathy and Emery-Dreifuss MD

Characterising proteomic effects of therapeutic compounds

 
  • Recent publications:

     

    Fuller HR and Morris GE (2012) “Quantitative proteomics using iTRAQ labeling and mass spectrometry” in Integrative Proteomics, InTech, ISBN: 978-953-51-0070-6.

     

    Humphrey EH, Fuller HR, Morris GE (2011) Current research on SMN protein and treatment strategies for SMA. Neuromuscular Disorders.  22(2):193-7.

     

    Comley LH†, Fuller HR†, Wishart TM, Mutsaers CA, Thomson D, Wright AK, Ribchester RR, Morris GE, Parson SH, Horsburgh K, Gillingwater TH (2011) ApoE isoform-specific regulation of regeneration in the peripheral nervous system. Hum Mol Genet. 2011(12):2406-2421.  † Denotes equal author contribution.

     

    Fuller HR, Man NT, Lam Le T, Shamanin VA, Androphy EJ and Morris GE (2010) Valproate and bone loss: iTRAQ proteomics show that valproate reduces collagens and osteonectin in SMA cells. J Proteome Res. 9 (8): 4228–4233.

     

    Fuller HR, Man NT, Lam le T, Thanh le T, Keough RA, Asperger A, Gonda TJ, Morris GE (2010) The SMN interactome includes Myb-binding protein 1a. J Proteome Res. 9(1):556-63.

     

    Walter MN, Wright KT, Fuller HR, Macneil S, Johnson WE (2010) Mesenchymal stem cell-conditioned medium accelerates skin wound healing: An in vitro study of fibroblast and keratinocyte scratch assays. Exp Cell Res. 316(7):1271-81. 

     

    Fuller HR, Marija B, Šimić Đurđica S, Špeljko T, Morris GE, Šimić G (2010) Treatment strategies for spinal muscular atrophy. Translational Neuroscience. 1(4):308-321.

     

    Fuller HR and Morris GE (2010) SMN complexes in the nucleus and cytoplasm as targets for SMA therapy: a proteomic study. Translational Neuroscience. 1(4): 261-267.

     

    Fuller HR (2010) Immunoassay and mass spectrometry studies of antigens in food. Basics, concepts and methods. Lambert academic publishing ISBN: 978-3-8383-4385-3.

     

     

     

     

     

     

     

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